HomeCommunityHealthFears grow genetically modified embryos could be created within months

Fears grow genetically modified embryos could be created within months

 

dna1Originally published in Christian Today

Fears are mounting that the genetic modification of human embryos could happen in British laboratories within months.

The fertility regulator will decide today whether scientists at the Francis Crick Institute can alter the genes of human embryos donated by IVF patients. If passed, the researchers will be the first in Britain to change an embryo’s DNA and only the second in the world.

Researchers say the move could help reduce miscarriage and improve IVF but critics fear it is the first step towards designer babies

However Nola Leach, CEO of Christian public policy charity CARE, said the proposals will have “completely unknown consequences for future generations”.

“We should not be experimenting with the sanctity of human life,” she told Christian Today.

The Human Fertilisation and Embryology Authority (HFEA) have been asked to grant permission for researcher Kathy Niakan to study how an embryo’s genes effect whether it survives the first week after conception. Less than one in two eggs survive the first week after fertilisation and just one in eight last the first three months of a pregnancy, according to the Mail Online.

Scientists say that learning more about this first week of life could spare more women the pain of miscarriage.

“The reason this is so important is that repeated miscarriages are unfortunately extremely common but they are not very well understood,” said Dr Niakan.

“One of the main aims is to understand these very early stages of human development.

“We believe this research could lead to improvements in fertility treatment, provide a really fundamental insight into some of the causes of miscarriage and a much deeper understanding of the earliest stages of human life.”

However Leach said although infertility was “heartbreaking”, there were other options such adoption or fostering.

“The Universal declaration on the human genome and human rights is explicitly clear that germ-line interventions could be judged as contrary to human dignity,” she told Christian Today.

“The UK should be talking to its international partners and discussing this issue rather than simply trying to be a trailblazer in this complicated area.

“We have already raised concerns about GM babies yet the pressure is still mounting and in the face of it all, we would urge the HFEA to stand firm and refuse this request.”

Dr Niakan wants to use a system known as CRISPR-Cas9 to target specific genes in the embryo and stop them working one by one. By doing this she hopes to identify which are key to an embryo’s early survival.

If scientists knew which genes were important, the information could be used to improve IVF as they could screen a woman’s embryo’s and implant only the healthiest. A faulty gene could also be tweaked or corrected.

However, this has given rise to fears that this could be a slippery slope towards genetically modifed embryos, which are currently illegal.

Dr Calum MacKellar, of the Scottish Council on Human Bioethics, told Mail Online the project opens the door to “full-blown eugenics”.

“The UK should not isolate itself and go it alone in making possible the gene editing of embryos,” he said. Instead, it should consult its international partners before making such an important and ground breaking decision which will have implications for the whole of humanity.”

 
 

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